Adaptive sequence evolution in a color gene involved in the formation of the characteristic egg-dummies of male haplochromine cichlid fishes-2
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paper
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WalIngAxe
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Taken from "Adaptive sequence evolution in a color gene involved in the formation of the characteristic egg-dummies of male haplochromine cichlid fishes"
BMC Biology 2007;5():51-51.
Published online 15 Nov 2007
PMCID:PMC2254590.
y, were not sequenced). (b) N/S ratio of haplochromines compared to non-haplochromine cichlids as revealed from a sliding window analysis with DNASP. (c) Schematic representation of the structure of the Csf1ra protein. The gene consists of an extracellular ligand-binding domain containing five immunoglobulin-like (Ig-like) domains with conserved cysteines (CYS), a transmembrane domain (TMD), and an intracellular partition that contains two tyrosine kinase (TK) domains interrupted by a kinase insert domain. In the tyrosine kinase I domain (TK I) a glycine-rich region (GLY-rich) and a conserved leucine (LEU) is found, the tyrosine kinase II domain (TK II) contains a conserved tyrosine (TYR). The asterisk indicates that in one species, , the otherwise conserved cysteine at amino acid position 450 has been replaced by a tryptophan. (d) Maximum likelihood phylogeny based on more than 4100 bp of non-coding sequences of the gene locus corroborating the monophyly of the haplochromines (yellow box) and the ancestral position of , , and [7]. The asterisk indicates relatively short branches not supported by high bootstrap values or a Shimodaira-Hasegawa test. (e) Branch-scaled tree showing the N/S rates reconstructed with HyPhy. The only internal branch with a N/S > 1 is the one representing the common ancestor of the haplochromines (yellow box).