This article presents a historical contribution of African Independent Churches in South Africa, particularly with references to the Ibandla lamaNazaretha of Isaiah Shembe, Zion Christian Church (ZCC) of Engenas Lekganyane and the St John’s Apostolic Faith Mission (AFM) of Christina Nku. There is no doubt that these churches continue to be attractive and relevant to the South African context in the 21st century. They form an integrated part of African Christianity in South Africa. The article investigates ways in which these churches respond to the spiritual and cultural needs of Africans. It is interesting to look at how the Holy Spirit, healing, prayer and prophecy manifest in these churches. The concept of African Spirituality is discussed and contextualised within these churches.