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Archaic introgression for HGDP and 1000genomes in hg38

Domain:

healthcare

Record type:

dataset
Creator:
Sko
Publisher:
Zenodo
Host:avatar
These files contain the infered positions of introgressed archaic sequence in 1000genomes and HGDP datasets. The segments are identified using hmmix (github.com). Datasets are phased so segments are infered for each haplotype. Each datasets will have two files: a *segments.txt file and a *SNPS.txt file.   > The columns in the segments.txt file are: name: name of individidualhaplotype: either hap1 or hap2 (if a genotype is 0|1 then 0 will be on hap1 and 1 will be on hap2)pop: population from HGDP or 1000 genomesregion: region from HGDP or 1000 genomes - can be AMERICA, CENTRAL_SOUTH_ASIA, EAST_ASIA, EUROPE, MIDDLE_EAST or OCEANIAchrom: chromosome in hg38 - X chromosome is not includedstart: start coordinate of introgressed segment in hg38end: end coordinate of introgressed segment in hg38mean_prob: Mean posterior probability that a segment is archaic according to hmmix (I usually recommend doing a cutoff at 0.8)ND_type: Which sequenced archaic does the segments share more derived SNPs with. Can be Both, Denisova, Neanderthal or nonesnps: Number of derived SNPs on segment NOT seen in Sub saharan Africaadmixpopvariants: How many derived SNPs are shared with a sequenced arhaic genomeAltai: How many derived SNPs are shared with the Altai Neanderthal (Denisova5)Vindija: How many derived SNPs are shared with Vindija Neanderthal (Vindija33.19)Denisova: How many derived SNPs are shared with Denisova (Denisova3)Chagyrskaya: How many derived SNPs are shared with Chagyrskaya Neanderthal (Chagyrskaya8)variants: List of derived SNPs on segment NOT seen in Sub saharan Africa    > The columns in the SNPS.txt file are: chrom: chromosome in hg38 - X chromosome is not includedpos: position of SNP in hg38 coordinatessnptype: can be shared derived with archaic (DAV), in high LD ancestralbase: what is the ancestral basederivedbases: What is the derived base (there can be multiple but >99% are bilallelic)freq_in_dataset: Frequency of most common derived base (in percent so the number is between 0 and 100)ND: derived in either Denisovans only (ND01), Neanderthals only (ND10), derived in both Neanderthals and Denisovans (ND11) or nonesharedwith: Which archaic genomes is the derived allele(s) shared with. This does not only include the four high coverage archaics    

Visit

doi.orgzenodo.org

Tags

introgressionNeanderthalDeniosvan

Licenses

Creative Commons Attribution 4.0 Internationalhttps://creativecommons.org/licenses/by/4.0/legalcode

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