This study explores the implementation and impact of personalized learning through artificial intelligence (AI) in Rwandan higher education, using a documentary research method. The analysis focuses on several key research questions: identifying the components of successful personalized learning models, examining their differences from traditional approaches, evaluating their impact on student engagement, motivation, and academic achievement, and understanding the challenges faced by educators, institutions and students. Findings reveal that successful personalized learning models in Rwanda feature customized curricula, adaptive instruction, competency-based progression, extensive use of technology, continuous assessments, and a learner-centered approach. These elements starkly contrast with traditional educational methods, which rely on standardized curricula, uniform instruction, time-based progression, limited technology use, periodic assessments, and a teacher-centered approach. Personalized learning significantly enhances student engagement and motivation by aligning learning experiences with individual needs and interests, leading to improved academic outcomes. AI assists in this process by providing real-time feedback, adaptive learning paths, and personalized content, thereby creating a more effective and efficient learning environment. However, the implementation of personalized learning and AI in Rwanda faces several challenges. Educators and institutions grapple with limited technological infrastructure, insufficient training, financial constraints, and resistance to change. Students encounter barriers such as limited access to technology, lack of digital literacy, and adaptation difficulties. To address these challenges, strategies include investing in technology, comprehensive training programs for educators, creating support systems for students, and developing robust data privacy and ethical use policies. In conclusion, personalized learning, supported by AI, holds promise for enhancing educational outcomes in Rwanda. It is recommended that universities and regulatory bodies prioritize investment in technology, educator training, and student support to effectively implement these innovative learning models.