Base scenario model parameters determined empirically for Baka Pygmies and Cameroon.
Domain:
healthcareRecord type:
WHO, 2012.
WHO Global Observatory Health Data Repository. World Health Organization, Geneva, Switzerland. http://apps.who.int/gho/dat…. Last accessed on 11/02/2012.
N: For the Cameroon-wide simulation to validate the model, a population of 200,000 was adopted, following Rupnow et al.[41].
Le: For the Baka, the Migliano et al. estimate for the Aka was used [52].
S5: Fraction of individuals that reach five years of age. For the Baka, no estimate was available, so the base scenario assumes that half of mortality that will occur by age 15 takes place by age 5, in keeping with typically high infant mortality in developing-world contexts.
S15: Fraction of individuals that reach fifteen years of age. For the Baka, the Migliano et al. estimate for the Aka was used [52].
NS: Fraction born non-susceptible, i.e., the fraction of individuals that cannot become infected “for physiologic, physical, or immunologic reasons” [41]. Estimated from observed maximum prevalences in the developing world.
βXY: = Transmission coefficients, with X and Y in {C,Y, A}, where these stand for child, youth and adult age classes, respectively, yielding nine coefficients in all. This represents the probability of transmission from class X to class Y, and is derived from Rupnow et al.[41], as described in the text.