Bayesian Ancestry-Stratified Allele Frequency Estimation for Pharmacogenomic Loci Underrepresented in gnomAD

Domain:

healthcare

Record type:

software

Creator:

SulOye

Publisher:

Host:

Code and analysis for a Bayesian hierarchical model that replaces point-estimate ACMG BA1/BS1 classification with calibrated posterior probabilities for pharmacogenomic alleles in African populations.

Visit

doi.org

Licenses

MIT License https://opensource.org/licenses/MIT

Hypertension in Colombia: First pharmacogenomic risk profile stratified by ancestry

# htn-gwas ## Purpose This study explores the influence of genetic ancestry on PGx risk profile re

AFA: Ancestry-specific allele frequency estimation in admixed populations: The Hispanic Community Health Study/Study of Latinos

Allele frequency estimates in admixed populations, such as Hispanics and Latinos, rely on the sam

A Curated Pharmacogenomic Allele Catalog for Sub-Saharan African Populations

Sub-Saharan African populations carry pharmacogenomic alleles poorly represented in the European-der

Cost-effectiveness of a Pharmacogenomic Test for Stratified Isoniazid Dosing in Treatment of Active Tuberculosis

Abstract Background There is marked interindividual variability in metabolism and resulting toxic

Tunisian population allele frequencies for 15 PCR-based loci

Allele Frequencies For 20 Autosomal Microsatellite Loci In The Kenyan Population

Abstract Samples from 180 unrelated persons of Kenyan descent collected at a DNA testing f