Chromosome position is based on the NCBI genome build 36.3;
2TM, Transmembrane domain; ECL, extracellular loop;
3Variant allele frequency (freq.) was obtained from participants in AIDS cohorts consisting of European American (EA) and African American (AA);
4Synonymous nucleotide T/C change at position 255 in the GenBank sequence U51241;
5Nucleotide G/A change at 2459 bp upstream of CCR5 ORF.