Chromosomal instability in Afrotheria: fragile sites, evolutionary breakpoints and phylogenetic inference from genome sequence assemblies-2

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Taken from "Chromosomal instability in Afrotheria: fragile sites, evolutionary breakpoints and phylogenetic inference from genome sequence assemblies"

biomedcentral.com

BMC Evolutionary Biology 2007;7():199-199.

Published online 24 Oct 2007

PMCID:PMC2211313.

details). The ancestral chromosomal forms corresponding to HSA 3/21 are represented as single conserved entities in the amniote, therian, eutherian and boreoeutherian ancestors. Source references for the species shown in the tree are: African elephant [23], domestic pig [84], rabbit [85], tree shrew [86], grey squirrel [87], domestic cat [88], aardvark [53], the xenarthran taxa the amadillo and lesser anteater [64], and the ENSEMBL genome database [82] for the rat, mouse, cattle, dog, opossum and chicken sequence alignments. The asterisks indicate the unequivocal identification of the HSA 3p/21 synteny based on reciprocal chromosome painting or data from the ENSEMBL genome database [82]. The estimated divergence dates follow [11]. The opossum and the chicken are included as representative outgroups species. Inset shows G-banding comparisons between elephant chromosomes 3 (LAF 3) and 21 (LAF 21) and aardvark chromosome 2 (OAF 2) showing the regions of homology to human chromosomes 3, 5 and 21 (HSA 3, HSA 5 and HSA 21); syntenic boundaries are derived from reciprocal chromosome painting data [23].