Using a quantitative methodology and a sample size of 300 respondents, this study investigates
the factors influencing consumer demand for over-the-counter (OTC) medications in Nigeria
from a microeconomic perspective. Price, income, perceived quality, trust, and substitute
preferences were all gathered through the use of a standardized questionnaire. To determine the
direction and intensity of the correlations between variables that impact the use of over-thecounter drugs, statistical analyses were performed using regression and correlation tests. The
results indicate that the quantity of OTC pharmaceuticals demanded is not significantly
influenced by price or income, reflecting the inelastic and necessity-based nature of healthrelated consumption in Nigeria. Weak but significant associations were also observed with nonprice criteria, such as perceived quality, trust in shops, and a desire for less expensive
alternatives, indicating that behavioral and informational elements have a modest influence on
purchasing decisions. These findings are consistent with other research, which shows that
perceived effectiveness and accessibility, rather than just economic rationale, frequently
influence healthcare spending in developing nations. The study concludes that the demand for
over-the-counter drugs in Nigeria is driven more by need than by financial means, highlighting
the need for affordability, consumer knowledge, and quality control. Policy implications
underscore the need for enhanced consumer education, more robust regulatory oversight, and
transparent pricing structures. By providing micro-level insights into self-medication behavior,
the study contributes to the growing empirical literature on health economics in emerging
markets. To investigate causal mechanisms in more depth and the effects of changing
pharmaceutical restrictions, future studies should expand the model to incorporate behavioral
tests, longitudinal data, and geographical comparisons.