Correlations between predictions and simulated gene expression measurements from simulated populations across various proportions of shared eQTL architecture with 20 causal cis-eQTLs.
Domain:
healthcareRecord type:
paper
Creator:
KevAngMarWal
Host:
(TIFF)
Similar
Distributions of t-statistics across various shared eQTL proportions for all nine train-test scenarios with 1000 Genomes populations for a fixed TWAS effect size and fixed number of causal eQTLs.Cross-population prediction performance across all five constituent GEUVADIS populations over genes with positive correlation between predictions and measurements.TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expressionPrediction R<sup>2</sup> between populations in GEUVADIS for genes with positive correlation between predictions and measurements.