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DATASET FOR FACTOR V LEIDEN IN SUBJECTS WITH PREECLAMPSIA

Domain:

healthcare

Record type:

dataset
Creator:
Aba
Editor:
AduAbiNarTet
Publisher:
Men
Host:avatar
In Ghana, there is limited information regarding factor V Leiden polymorphism on the pathogenesis of preeclampsia (PE) and its associated outcomes; hence, the focus of the current study. Eighty-one (81) consented subjects were recruited after ethical clearance was obtained and structured questionnaire administered to them. Routine blood chemistry and characterization of Factor V Leiden were obtained for subjects. We found FVL mutation much more in PE and hypertensive patients. FVL exon 10 were 0.67 and 0.33 for G and A alleles respectively. There was an absence of FVL mutation in exon 8 in the current study. Increased white blood cells, increased uric acid and a three – fold increment of AST / ALT ratio were observed among PE cases when stratified by FVL exons (exon 8 and 10). This study was the first to report baseline FVL genotypic and allelic frequencies as well as relating clinical variables with it.

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data.mendeley.com

Tags

Coagulation Factor V

Licenses

Creative Commons Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0

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