The first introduction of robot wives on African soil can come soon as a solution to lack of companionship. This Opinion looks at the potential effect the introduction of artificial intelligence powered humanoid robot wives will have on the genetic population and gene pool across the African continent. The effect of the introduction of robot wives will depend on the level of prevalence of exclusive biological male and robot wife mating’s. High prevalence of exclusive biological male and robot wife mating’s can result in genetic drift and genetic erosion. Low prevalence of exclusive biological male and robot wife mating’s will have a minuscule effect on the genetic population gene pool and structure. Ubiquitous presence of robot wives across the continent can result in a negative eugenics effect that can lead to loss of genetic variation and low human population growth rates, affecting the African demographic structure. This opinion is meant to ignite discussion and debate on the concept of robot wives on the African Continent in the event that the humanoids eventually are introduced.