Epidemiological Trends in Acute Kidney Injury in Senegal: A Scoping Review Protocol

Objective: This scoping review aims to map and characterize the available literature on acute kidney injury (AKI) in Senegal and to describe the epidemiological, etiological, and prognostic trends reported in hospital settings while identifying gaps in the existing evidence. Introduction: Acute kidney injury is a major public health concern because of its high morbidity, risk of progression to chronic kidney disease, and associated mortality. Most available evidence originates from high-resource settings, while consolidated data from Senegal remain limited. Grey literature, particularly academic theses and dissertations, represents an important source of information for reconstructing the epidemiological evolution of AKI in the country. Inclusion criteria: This review will include studies involving hospitalized adult and pediatric patients with a documented episode of acute kidney injury. It will examine the epidemiological, etiological, and prognostic characteristics of AKI reported in Senegalese hospitals. Studies exclusively involving patients with chronic kidney disease without acute kidney injury and studies conducted outside hospital settings will be excluded. Methods: The review will follow the Joanna Briggs Institute (JBI) methodology for scoping reviews and will be reported according to the PRISMA-ScR guidelines. Evidence sources will include university and hospital libraries in Senegal, institutional reports, and academic search engines, including Google Scholar. Study selection will be conducted in two stages (title/abstract screening followed by full-text review) by two independent reviewers. Data will be extracted using a standardized data-charting form. Findings will be synthesized descriptively to map the epidemiology of AKI and assess temporal trends in etiologies, mortality, and dialysis utilization. Where data are sufficiently homogeneous, descriptive quantitative analyses and meta-analyses will be performed.