abuzumeran/Meta-Analysis-in-R

Meta-Analysis of HRQoL among Menopausal Women in Sub-Saharan Africa Meta-Analysis of HRQoL among Menopausal Women in Sub-Saharan Africa This repository contains the R code used to perform a systematic meta-analysis on the Health-Related Quality of Life (HRQoL) scores among menopausal women in the Sub-Saharan African region. Project Overview The study pools mean HRQoL scores from various standardized tools (MRS, MENQOL, UQoL, etc.) by normalizing them to a 0–100 scale. Key Analysis Features: • Normalization: Standardizing different psychometric scales to a uniform 0-100 metric. • Pooling: Random-effects meta-analysis using the meta package. • Sensitivity: Leave-one-out analysis to ensure robust results. • Subgroup Analysis: Investigating variations by Country, Tool, Menopausal Stage, and Study Quality. • Meta-regression: Assessing the impact of Publication Year and Sample Size. • Publication Bias: Funnel plots (contour-enhanced), Egger's test, and Trim & Fill adjustment. Requirements To run this script, you will need R and the following libraries: • meta • metafor • dplyr • readxl • ggplot2 Usage 1. Clone this repository. 2. Ensure your data follows the structure expected in the script (refer to the read_excel section). 3. Update the file_path variable in the script to point to your local data file. Author Abuzumeran A. Mohammed PhD Candidate Haramaya University