armel001/Guinea-SARS-CoV2-Spatiotemporal

Repository for COVID-19 data analysis and publication resources ## Associated Publication This repository is linked to the following peer-reviewed publication: Gnimadi T.A.C., Kadio K.J.-J.O., Mathew M.J., Diallo H., Soumah A.K., Keita A.K., Hounmenou C.G., Fernandez-Nuñez N., Vidal N., Guichet E., et al. *Genetic Diversity and Spatiotemporal Distribution of SARS-CoV-2 Variants in Guinea: A Meta-Analysis of Sequence Data (2020–2023).* Viruses. 2025; 17(2):204. mdpi.com ### Study Overview This study describes the genetic diversity and spatiotemporal distribution of SARS-CoV-2 variants circulating in Guinea during the COVID-19 pandemic using publicly available viral genome sequences collected between March 2020 and December 2023. ### Key Findings - A total of 1,038 SARS-CoV-2 genomes generated in Guinea were analyzed. - 73.1% of sequences corresponded to Variants of Concern (VOCs), including: - Omicron (69.4%) - Delta (21.9%) - Alpha (6.6%) - Eta (2.1%) - Phylogeographic analysis identified 75 viral importation events into Guinea: - 40% from Africa - 25.3% from Europe - 18.6% from Asia ### Impact The findings highlight the importance of large-scale genomic surveillance to better understand viral evolution, variant dissemination, and cross-border transmission dynamics in West Africa.