Bosskhan/Upper-respiratory-microbiome-composition-and-pneumococcal-colonisation-in-The-Gambia
Domain:
healthcareCreator:
Bos
Host:
Description of the upper respiratory tract microbiome of children 5-14 years old in The Gambia
# Gambia-URT-microbiome-pneumococcal-colonisation
Upper respiratory tract bacterial microbiome features associated with
Streptococcus pneumoniae colonisation and environmental factors among healthy
older children in a rural setting in The Gambia.
**Status:** Manuscript in preparation.
**Code:** The analysis code will be published here once the manuscript is
submitted.
## Summary
This project characterises the upper respiratory tract (URT) bacterial
microbiome of healthy children aged 5–14 years in The Gambia, sampled
longitudinally over eight visits, using 16S rRNA sequencing alongside
culture-based detection of *S. pneumoniae*. The analysis explores microbiome
composition and temporal dynamics in this age group, and their relationship
to pneumococcal colonisation status, age, and season.
## Contact
Questions about this project can be directed to dam.khan@lshtm.ac.uk.
Similar
Impact of viral upper respiratory tract infection on the concentration of nasopharyngeal pneumococcal carriage among Kenyan childrenPulmonary non-tuberculous mycobacteria in The Gambia: colonisation and clinically-relevant diseaseHousehold composition and the infant fecal microbiome: The INSPIRE studyLongitudinal Changes in the Composition of the Penile Microbiome Are Associated With Circumcision Status, HIV and HSV-2 Status, Sexual Practices, and Female Partner Microbiome CompositionPneumococcal carriage in rural Gambia prior to the introduction of pneumococcal conjugate vaccine: a population‐based surveyPneumococcal conjugate vaccination in The Gambia: health impact, cost effectiveness and budget implications