brsaran/IndiaCanStage

A low-resource, rule-based cancer staging platform enabling automated AJCC (8th & 9th), Essential TNM, and SEER Summary Stage derivation for registries and clinical use. # India-Can-Stage **India-Can-Stage** is a low-resource oriented digital cancer staging platform developed to support standardized cancer staging for **hospital-based and population-based cancer registries** and to aid **clinical decision-making** in India and similar LMIC settings. The tool implements **deterministic, rule-based staging logic** derived from **AJCC 8th and 9th edition guidelines** and enables automated derivation of multiple staging systems from structured clinical inputs. --- ## Key Features - **Supports 44 cancer sites** relevant to Indian cancer registries - **Single data entry** generates staging outputs for both **AJCC 8th and 9th editions** - Generates: - **AJCC TNM** - **AJCC Composite Stage Group** - **Essential TNM (ETNM)** - **SEER Summary Stage (SSS)** - **Rule-based deterministic engine** ensuring reproducible and auditable results - **Built-in validation** to prevent invalid or unrealistic TNM combinations - Incorporates **AJCC-defined site-specific prognostic variables**, including: - **Age** (thyroid cancer) - **PSA** (prostate cancer) - **Tumor grade** (appendix, prostate, bone) - **Serum markers** such as **LDH, AFP, and hCG** (testicular cancer) - Designed for **low-resource settings** with incomplete clinical documentation - **Modular architecture** enabling easy updates for future AJCC revisions --- ## System Architecture - **Backend**: Python 3.12–based modular rule engine - **Frontend**: Streamlit-based interactive interface - **Logic Layer**: Site-specific AJCC rule matrices - **Output**: Structured **JSON** for interoperability The architecture ensures **transparency, traceability, and scalability**, enabling deployment across hospitals, registries, and academic institutions. --- ## Web Application A fully functional web deployment of **India-Can-Stage** is currently available. **India-Can-Stage Web Application:** Access the webversion here India-can-Stage. The production system is centrally hosted on secure **IC …