HemaPath Interpreter v2.0 is an offline-first, federated AI for hematopathology. It scales from $50 smartphones (Tier 1) to digital centers (Tier 4). Using foundation model ensembles and a shared clinical protocol, it delivers expert PBF, BMA, and histology insights in low-resource settings. Global care, simplified.
# HemaPath Interpreter v2.0 — Master Install & Usage Guide
> **A tiered, offline-first, federated hematopathology AI platform
> for low- and middle-income settings and beyond.**
> EEHLSS / Alafia AI · Apache 2.0 · April 2026
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## 0. What is HemaPath Interpreter v2.0?
HemaPath Interpreter v2.0 is an integrated clinical-AI platform for **peripheral blood film (PBF/PBS)**, **bone marrow aspirate (BMA)**, **bone marrow trephine biopsy**, and **lymph node histology** interpretation. It pairs a **protocol-driven reasoning skill** with an **ensemble of state-of-the-art open-source pathology foundation models** (TRIDENT · UNI-v2 · CONCH-v1.5 · TITAN · DINOBloom · RedDino · CellViT++ · HoVer-NeXt · YOLO26), and is deployable from **a $50 smartphone** up to a **$200K+ comprehensive digital-pathology centre**.
It supersedes two earlier reference architectures:
| Predecessor | Strength | Weakness |
|---|---|---|
| **HemaPath v1 skill** (this repo) | Rich clinical reasoning protocol | No deployment paths for low-resource sites |
| **PathologyAI deploy bundle** (React/Node/K8s + OpenAI) | Full web app + K8s auto-scale | Online-only; OpenAI-dependent; wrong fit for LMIC edge |
v2.0 merges the clinical depth of v1 with a **tier-aware deployment fabric** that runs **offline-first at Tier 1–2**, **hybrid at Tier 3**, and **fully orchestrated at Tier 4**.
See `docs/01_ARCHITECTURE_COMPARISON.md` for the full three-way comparison.
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## 1. Pick your tier
```
┌──────────────────────────────────────────────────────────────────────────┐
│ WHICH TIER IS RIGHT FOR ME? │
├──────────────────────────────────────────────────────────────────────────┤
│ │
│ Do you have any computer with a GPU or can you buy a $250 Jetson? │
│ │
│ No ─► Tier 1 (Smartphone) …