omicscodeathon/phylotools_sars2

Comparative Study between Molecular and Genetic Evolutionary Analysis Tools Using African SARS-CoV-2 Variants # Comparative Study between Molecular and Genetic Evolutionary Analysis Tools Using African SARS-CoV-2 Variants #### Our Team. Lead: Nouhaila En najih, Awe Olaitan, Marion Nyaboke Nyamari- Writers: Latifah Benta Mukanga ## Abstract Phylogenetic analysis is considered to be a highly reliable and important bioinformatics tool. Currently we have many phylogenetic tools that biologists can use to interpret and visualize biological data. However, most of these tools require a lot of expertise and technical know-how for one to be able to use them. In this study, African SARS-CoV-2 Variants are used to compare three phylogenetic tools (MEGA, SeaView and Geneious) in terms of their ease of use, output and accessibility. ## Methods ### Data Collection The SARS CoV 2 complete genome sequences from different countries in the South African region were retrieved from the NCBI Virus repository (www.ncbi.nlm.nih.gov, n.d.) in fasta format. ### Data Preprocessing ### Phylogenetic Analysis #### MEGA MEGA11 is available for Microsoft Windows, Linux, and macOS in natively developed graphical user interface and command-line versions at www.megasoftware.net. Both 32- and 64-bit versions of MEGA are available for download. #### SEAVIEW SeaView workflow manager can be installed on Microsoft Windows,Mac OS X,Linux and Solaris through doua.prabi.fr. #### GENEIOUS ## Results ## Team * Olaitan I. Awe, African Society for Bioinformatics and Computational Biology, laitanawe@gmail.com * Nouhaila En najih, Systems and Data Engineering team, National School of Applied Sciences, Abdelmalek Essaadi University,Tangier, Morocco, nouhailaennajih25@gmail.com * Marion Nyaboke Nyamari, School of Pure and Applied Sciences, Pwani University, Kenya, marionnyaboke01@gmail.com * Latifah Benta, Department of Life Sciences, South Eastern Kenya University, Kitui,Kenya, latifahmukanga@gmail.com