Following the indications reported in Task 6.3.5 of the MADFORWATER project, MADFORWATER partners dedicated a relevant effort to the development of guidelines for the adaptation to other basins in Morocco, Egypt and Tunisia and to other MENA countries of the MADFORWATER tools, technologies and approaches. The general goal of these guidelines is to allow a generic stakeholder (such as a manager of a wastewater treatment plant, a wastewater company, an irrigation company, a farmer, the director of a basin authority, an officer of the Ministry of Irrigation) to perform the necessary activities in order to adapt the MADFORWATER technologies and water management tools to the specific context in which the considered technology or tool needs to be implemented. The adaptation guidelines developed in the framework of MADFORWATER and presented in this deliverable are relative to (i) the MADFORWATER approach for the analysis of water security, (ii) the project’s technologies for wastewater treatment and irrigation, and (iii) the two MADFORWATER decision support tools for wastewater management and for water & land management in agriculture. With regard to these two decision support tools, the adaptation guidelines are integrated by the description of the structure of two training courses that the MADFORWATER partners FHNW, IAMB and UPM can offer to potentially interested stakeholders. The adaptation guidelines presented in this deliverable are integrated by a consistent amount of material – such as the user manuals and computer codes for the decision support tools, the detailed description of the MADFORWATER approach for the assessment of water security and the fact-sheets of the MADFORWATER technologies – freely accessible to any interested stakeholder through the MADFORWATER website or the repositories in which the MADFORWATER dataset have been deposited (mainly, AMS Acta and Zenodo). The links for the direct download of this material are systematically reported in this deliverable.