<p>Malaria remains a major health problem predominantly in tropical countries and is still being one of the biggest causes of mortality worldwide. It is an ancient vector borne infectious disease caused by parasitic protozoans of the genus <em>Plasmodium</em> and is transmitted by female mosquitos of the <em>Anopheles</em> species. The spatiotemporal distribution of this vector is sensitive to climate conditions and the distribution of hydrometeorological variables, particularly temperature, precipitation, and humidity. We present first results of a joint high resolution hydrometeorological- and subsequent dynamical vector transmission modelling. Our approach uses the couple atmospheric- and terrestrial model system WRF-Hydro, with a 1km grid spacing for the atmospheric part and a 100m grid spacing for the hydrological part. Besides traditional hydrometeorological variables, WRF-Hydro further resolves the surface water, which is potentially a crucial step forward for the grid cell distributed dynamical vector transmission model VECTRI. Our study addresses two Health and Demographic Surveillance Systems (HDSS) site regions at Nouna in Burkina Faso and Kisumu in Kenya. We present an analysis of the performance of the hydrometeorological model system and first results of the VECTRI modeling.</p><p>Preliminary results of the WRF-Hydro -VECTRI model system capture the Malaria seasonal variations correctly and show reasonable reproduction of the year-to-year variability of HDSS observed total Malaria cases.</p>