High-throughput sequencing of the B-cell receptor in African Burkitt lymphoma reveals clues to pathogenesis
Domain:
healthcareCreator:
KatDavAliChr
Publisher:
Ame
Host:
Key Points
High-throughput sequencing of primary African Burkitt lymphoma tumors suggests disrupted immunoglobulin rearrangements in BL progenitors. Extensive mutation of expressed and nonexpressed IGH rearrangements suggests multiple active mutational processes in BL tumors.
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