Insecticide resistance and species diversity in Anopheles gambiae s.l. in Côte d'Ivoire

This dataset accompanies the study “Insecticide resistance and species diversity in Anopheles gambiae s.l. in Côte d’Ivoire.” The study investigated insecticide resistance phenotypes, target-site mutations, and species distribution in malaria vectors collected across three ecological zones (savannah, pre-forest, and forest) in Côte d’Ivoire between July and October 2020. Mosquito larvae and adults were sampled and analyzed using WHO susceptibility bioassays with pyrethroids (deltamethrin, permethrin) and an organophosphate (pirimiphos-methyl), complemented by synergist assays with piperonyl butoxide (PBO) and resistance intensity assays at 5x and 10x diagnostic doses. Molecular analyses included PCR-based species identification and genotyping for Kdr L1014F and Ace-1R G119S mutations. The dataset provides raw and processed data on: Species composition across ecological areas, Mortality outcomes from bioassays, Resistance intensity and synergist effects, Allelic frequencies of resistance-associated mutations, GPS coordinates of mosquito sampling sites across study areas. These data support evidence of significant ecological variation in both vector species distribution and resistance mechanisms, with implications for malaria control strategies in Côte d’Ivoire.Funding: This work was supported by a grant awarded to the Institut Pierre Richet / Institut National de Santé Publique, Côte d’Ivoire, from the Bill & Melinda Gates Foundation (OPP1210335) through the Pan African Mosquito Control Association (PAMCA)