This study attempts to account for the analysis of the interaction between the syntactic structure and the semantic outcome of serial verb constructions in Mə̀dʉ́mbɑ́, an East Grassfields Bantu language spoken in the Nde division, WestRegion of Cameroon. It builds from natural data collected from field informants and native speakers’ intuitive knowledge of the language to provide an in-depth descriptive analysis of Mə̀dʉ́mbɑ́ serial verb constructions from a morpho-syntactic and semantic perspective. In this view, the article examines the structural characteristics of SVCs in the language and brings up a semantic typology of SVCs in Mə̀dʉ́mbɑ́. The discussion of the morpho-syntactic manifestation of SVCs goes in line with Ameka (2005) while the overall analysis is undertaken from a descriptive grammar perspective. The paper also attempts a compositional semantic analysis of SVCs in the language.