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Linezolid Population Pharmacokinetics in South African Adults with Drug-Resistant Tuberculosis

Domain:

healthcare

Record type:

paper
Creator:
MahSeaJamKee
Publisher:
Ame
Host:
Linezolid is widely used for drug-resistant tuberculosis (DR-TB) but has a narrow therapeutic index. To inform dose optimization, we aimed to characterize the population pharmacokinetics of linezolid in South African participants with DR-TB and explore the effect of covariates, including HIV coinfection, on drug exposure.

Licenses

https://doi.org/10.1128/ASMCopyrightv2https://journals.asm.org/non-commercial-tdm-license

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