Globalization integrates the whole world into a global village. The opening up of economies to international trade is expected to lead to growth and poverty reduction. However, the benefits of globalization have been disproportionately skewed towards developed economies. Despite opening its economies to foreign goods and integrating to the global market, Africa remains the poorest region in the world. Xenophobia in Africa has particularly been a major concern as African migrants within the continent have been experiencing various forms of hostilities and xenophobic attacks. Many authors agree that globalization and economic inequality contribute to this trend. This chapter analyzes from an Afrocentric perspective, the various social, economic, and historical context in which globalization and other European capitalist quests in Africa affect migration pattern in the continent and contribute to xenophobia in Africa. This chapter provides an Afrocentric critique of the idea of globalization which mainly promotes free trade and capital but restricts the movement of African labour.