These data are from a cross-sectional survey conducted among healthcare providers providing oral pre-exposure prophylaxis (PrEP) services and healthcare providers who would be providing oral PrEP services in the near future in Kenya. The study was conducted in 16 health facilities in 4 counties of Kenya in 2018. The dataset includes information on providers’ familiarity and knowledge of PrEP and their attitudes and beliefs towards PrEP delivery to target populations, specifically adolescent girls and young women.