Pathways among gene, metabolite, risk factor and disease identified among ARIC African Americans.

Domain:

healthcare

Record type:

dataset

Creator:

BinYanDanAla

Host:

Solid arrows between genes and metabolites indicate genome-wide significant effects (p<1.6×10⁻¹⁰). Arrows between metabolites and risk factors indicate significant linear associations after adjusting for age and gender (p<0.05). Arrows between metabolites and clinical endpoint indicate significant associations after adjusting for age, gender and other risk factors using Cox proportional hazards modeling (p<0.05). The dotted arrows between risk factors and clinical endpoints indicate well-established relationships. DBP indicates diastolic blood pressure and eGFR, estimated glomerular filtration rate.

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