Phylogenetic analysis of the DENV2 Cosmopolitan genotype in Angola.

A. Maximum likelihood (ML) phylogenetic tree with reference DENV2 genotype strains from [33] suggesting clustering of the Angola strains within the DENV2 Cosmopolitan genotype. Numbers indicate bootstrap support for phylogenetic clustering. The inset on the lower left corner shows the strong correlation between root-to-tip divergence and sampling dates for a ML phylogenetic tree estimated from an alignment comprising the Angola strains and the closest publicly available DENV2 Cosmopolitan genotype strains (n = 38). B. Dated phylogeographic tree of DENV2 Cosmopolitan genotype genomes with branches colored according to locations where strains were sampled. At the righthand side of each sequence, squares show sample type according to origin of sample. Arrow on the right highlights the most recent sample, B09 isolate, collected in the Cunene province in February 2019. s/s = substitutions per site; R = correlation coefficient.