These data include epidemiological profiles derived from a community household study of respiratory syncytial virus in coast Kenya. The original datasets have been described previously in http://doi.org/10.1093/infd… and http://doi.org/10.1093/ve/v… but in brief, swabs were collected twice weekly from all members of 47 households in Kilifi County, Kenya during the RSV season from December 2009 until June 2010. The datasets included in this repository are largely variant calls made from short read sequence data using a number of variant callers. In addition, we have included whole genome phylogenetic trees from three households and which have been described previously.