Replication Data for: Biomarkers of post-discharge mortality among children with complicated severe acute malnutrition

This was a nested case control study within a clinical trial (NCT00934492) that tested the efficacy of daily co‐trimoxazole prophylaxis in reducing post‐discharge mortality among HIV‐uninfected children aged 2-59 months hospitalised with CSM in two urban (Mombasa and Nairobi) and two rural (Kilifi and Malindi) hospitals in Kenya. We investigated mechanisms underlying early post-discharge mortality (<60 days) using untargeted plasma proteome, targeted cytokines/chemokines, leptin, and soluble CD14 (sCD14) measured after hospital stabilisation (at discharge).

Data package includes:

1. Njunge_Sci_Rep_s41598-019-42436-y.dta and (b) Njunge_Sci_Rep_s41598-019-42436-y.csv: Both files contain similar information. The files contains anthropometric at the time of hospital discharge for study children. It also contains full blood count at enrolment. Anthropometric z scores calculated using 2006 WHO growth references. Study data were entered into OpenClinical trial database. After locking the trial database, the data were extracated and exported to STATA Version 15.1 for statistical analysis.
2. Njunge_Sci_Rep_s41598-019-42436-y.do This analysis script is used to generate the summary participants characteristics at enrolment and conduct regression analysis.
3. Data Dictionary: contains variable descriptions and value labels

Data Access: Open License: Creative Commons Attribution 4.0 International