Replication Data for: Lifelong malaria exposure drives B cell activation and post-transcriptional regulation while suppressing inflammatory transcriptional programs

Domain:

healthcare

Record type:

dataset

Creator:

KimMwiMudMut

Editor:

KimNduThe

Publisher:

Har

Host:

This is a replication dataset for the manuscript titled: "Lifelong malaria exposure drives B cell activation and post-transcriptional regulation while suppressing inflammatory transcriptional programs ."

This dataset was generated as part of a study investigating immunological signatures associated with lifelong malaria exposure among healthy adult participants from Kenya. It includes data collected across multiple malaria transmission settings and comprises:

Baseline participant characteristics (e.g., age, sex, site)
Raw and processed cytokine measurements from plasma samples
Raw and normalised RNA-seq counts from peripheral blood mononuclear cells (PBMCs), including both unprocessed gene-level counts and counts normalised to counts per million (CPM)
An R Markdown file with annotated statistical code used for data processing and analysis

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doi.org dataverse.harvard.edu

Licenses

info:eu-repo/semantics/restrictedAccess Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode

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