Results of qByte for nucleic acid tests.
Domain:
healthcareRecord type:
A: Benchmark of the qByte and a commercial thermocycler for performing isothermal amplifications using GMO detective reactions [30]. B: Time-to-threshold comparison. C: Further validation using CoronaDetective reactions [31] (top) and previously developed LAMP reactions for Schistosoma mansoni detection, performed on-site at a healthcare facility in Ghana (bottom). D-E: Benchmark of the qByte for non-amplification detection using Cas12a with synthetic Salmonella enterica serovar Typhi (S. typhi) DNA (D) and Zika virus RNA fragment detection via activation of an RNA toehold (E). F-G: Analysis of the impact on the melting curve of different oligo sizes (F) and the effect of increasing mismatch mutations (G). The raw data supporting all figures can be found in S2 File.