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Robust control strategy by the Sterile Insect Technique for reducing epidemiological risk in presence of vector migration

Domain:

healthcare

Record type:

paper
Creator:
BliDum
Editor:
ModBotAMADép
Publisher:
CCSDElsevier
Host:avatar
International audience The Sterile Insect Technique (SIT) is a promising technique to control mosquitoes, vectors of diseases, like dengue, chikungunya or Zika. However, its application in the field is not easy, and its success hinges upon several constraints, one of them being that the treated area must be sufficiently isolated to limit migration or re-invasion by mosquitoes from the outside. In this manuscript we study the impact of males and (fertile) females migration on SIT. We show that a critical release rate for sterile males exists for every migration level, in the context of continuous or periodic releases. In particular, when (fertile) females migration is sufficiently low, then SIT can be conducted successfully using either open-loop control or closed-loop control (or a combination of both methods) when regular measurements of the wild population are completed. Numerical simulations to illustrate our theoretical results are presented and discussed. Finally, we derive a threshold value for the females migration rate, when viruses are circulating, under which it is possible to lower the epidemiological risk in the treated area, according to the size of the human population.

Visit

hal.science

Tags

Sterile Insect TechniqueMigration ratesPeriodic impulsive controlOpen-loop and closedloop controlCritical release rate[MATH.MATH-OC]Mathematics [math]/Optimization and Control [math.OC][SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie

Licenses

https://about.hal.science/hal-authorisation-v1/info:eu-repo/semantics/OpenAccess

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