Steep Rebound of Chloroquine-Sensitive<i>Plasmodium falciparum</i>in Zimbabwe
Domain:
healthcareRecord type:
paper
Creator:
SunZviNobCha
Publisher:
Oxf
Host:
Abstract Removal of chloroquine from national malaria formularies can lead to the reversion of resistant Plasmodium falciparum to wild-type. We report a steep decline in chloroquine-resistant P falciparum within 10 years of national discontinuation of chloroquine monotherapy in Zimbabwe. Drug resistance surveillance is a vital component of malaria control programs, and the experience with chloroquine in Zimbabwe and elsewhere in sub-Saharan Africa is illustrative of the potentially rapid and dramatic impact of drug policy on antimalarial resistance.
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