Transmission dynamics of Ebola virus disease and intervention effectiveness in Sierra Leone
Domain:
healthcareRecord type:
paper
Creator:
Li‐YanJiaHon
Publisher:
Nat
Host:
Significance
Since the initial recognition of Ebola virus disease (EVD) in 1976, many epidemics have occurred in Africa. Serious concerns remain that the fatal disease may repeatedly reemerge. In this study, we used data from an unprecedented EVD outbreak in Sierra Leone to map spatiotemporal transmission patterns, identify influential factors, and assess the effects of interventions at the chiefdom level. Furthermore, we have quantified household transmissibility and the temporal association between interventions and household transmission. Our findings have deepened the understanding of the transmission dynamics of EVD and provided key information for future modeling efforts in forecasting future epidemics and establishing intervention strategies.
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