This chapter outlines aspects of understanding epilepsy from an African perspective. The chapter starts by introducing the condition of epilepsy and what research says nationally and internationally with definitions from various views. Furthermore, the chapter discusses causes, symptoms, and impact on children. This chapter highlights the definition of epilepsy and describes epilepsy from various African languages and perspectives. The chapter also shows that epilepsy in children is associated with problems in multiple areas such as their academic achievement, behavioural and emotional adjustments, and social competence. The chapter reports that students with epilepsy often experience negative social consequences due to their condition, and that teachers can do several things to help minimise and assist the children to reach their full potential. In conclusion, the chapter discusses and suggests effective strategies to manage and support the condition.