This dataset contains four fully anonymized qualitative interview transcripts with married couples experiencing infertility. The data was collected in Takoradi, Ghana. The interviews explore the lived psychosocial experiences of infertility, covering themes such as emotional distress, marital dynamics, social stigma, cultural and religious influences, coping strategies, and sources of hope. All direct identifiers have been removed or generalized to protect participant confidentiality. The transcripts are provided in English and are intended for secondary analysis in qualitative research related to infertility, global health, psychosocial well-being, and cultural studies.