(A) Boxplot of the age at onset of patients with the homozygous genotype GG and of A-carriers. p = 0.04, unpaired two-sided t-test. (B) Curves of the cumulative breast cancer incidence at the indicated age at onset of GG patients and of A-carriers. p = 0.01, log-rank test. A-carrier, patients with the GA (n = 93) or AA (n = 11) genotype.