Rapid AI advances have introduced intelligent tutoring in classrooms worldwide. UNESCO and OECD emphasize AI’s promise for personalized, inclusive learning while cautioning that teachers should not be displaced. With UNESCO projecting a 44 million teacher shortfall by 2030, assessing AI tutors’ roles relative to human instruction is urgent. We synthesize research, global case studies (US, China, India, Europe, Africa), and policy reports to compare AI tutors and human teachers in general education. Focus areas include instructional effectiveness, emotional/social impact, cost and scalability, accessibility and inclusion, and hybrid teaching models. A systematic review of literature and case analyses was conducted, including empirical studies and UNESCO/OECD policy documents, to distill insights across diverse contexts. Studies show AI tutors can boost learning outcomes. For example, one randomized trial found students learned significantly more and faster with an AI-powered tutor than in active classroom instruction. AI systems deliver scalable, cost-effective personalization, helping reach underserved students and bridge equity gaps. UNESCO notes AI’s role in aiding learners with disabilities or language needs, promoting inclusion. However, AI cannot match the empathy and social support of human teachers. Hybrid approaches combining AI and human tutoring yield synergistic gains, especially for lower-achieving learners. AI tutors and human teachers are complementary. Effective education leverages AI’s personalization and reach alongside human empathy and guidance. Thoughtful hybrid models and policies that support teacher roles are key to maximizing learning outcomes and equity.