According to Blue Cross Kenya (BCK) project’s theory of change, a comprehensive prevention approach can produce mutually reinforcing effect to reduce risk factors and enhance protection factors related to substance use and mental health. The three main areas are: 1) Influencing leaders and authorities on policy issues regarding alcohol and mental health. 2) Life-skills education through 30 school clubs and 4 youth centers, with about 2,000 participants. Life skills include processes that contribute positively in the development of children and young people and thus also give them resources to withstand challenges in life. Parents and teachers also receive guidance to strengthen protection factors. 3) Mobilization of children and young people, parents, communities, and other organizations