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Taken from "Characterization of Atrazine-Induced Gonadal Malformations in African Clawed Frogs () and Comparisons with Effects of an Androgen Antagonist (Cyproterone Acetate) and Exogenous Estrogen (17β-Estradiol): Support for the Demasculinization/Feminization Hypothesis"
Environmental Health Perspectives 2006;114(S-1):134-141.
Published online 24 Jan 2006
PMCID:PMC1874169.
This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI
The individual shown was exposed to 0.1 ppb atrazine. Abbreviations: K, kidney; O, ovary; UO, unpigmented ovaries. () The entire dissected, Bouin’s-fixed kidney–interrenal–gonadal complex. Although the individual shown has distinct lobes, some animals with this morphology had only very shallow indications of lobes. () A transverse cross-section (8 μm) through the geometric center of the animal’s kidney and gonads. The section is stained in Mallory’s trichrome stain. This histology revealed that the animals were in fact females, even though their gonads lacked pigment, typical of normal ovaries. Scale bar: () 0.1 mm; () 40 μm.