Antibiogram and Molecular Analysis of Clinical Bacteria Isolates from the Three Geographical Regions of Ondo State, Nigeria

This study shows diversified forms of multidrug resistant aetiologic agents that were obtained from designated health centers in Ondo State, Nigeria. One hundred and fifty (151) clinical microbial isolates collected from designated health centers/hospitals in Ondo, Okitipupa, Owo and Akure were identified. From Ondo North (SSH, Ikare and FMC, Owo), Seventy (70) bacterial isolates were obtained and this includes 15 (21.4%) Gram +ve organisms consisting of Staphylococcus spp, Bacillus spp, Streptococcus spp, and Corynebacterium spp. While 55 (78.6%) of the isolates were Gram-ve of various species. In Ondo Central (SSH, Akure and Trauma Centre, Ondo), Sixty-five (65) bacterial isolates obtained comprises 16 (24.6%) Gram+ve species of Staphylococcus and Streptococcus only. While 49 (75.4%) were Gram-ve bacterial species. Similarly, Ondo South (SSH, Okitipupa), Thirty-three (33) bacterial isolates were obtained, 8 (24.2%) were Gram+ve of the species of Staphylococcus, Streptococcus and Enterococcus. While 25 (75.8%) were Gram-ve of diverse species. Thirty two (32) of 151 bacterial isolates subjected to antibiotic susceptibility test were extremely resistant to both the convectional antibiotic discs and the E-tests strips. These resistant strains were further identified molecularly with their plasmid profile studied for clinical purposes. Amp gene coded for antibiotic resistance was detected in some of the bacterial isolates tested among other observations. This is of epidemiological significance and shows the necessity to sort alternative therapy for these multiple antibiotic resistant strains and improve our health management services.