Estimates of HIV-1 C effective number of infections (Ne) over time from 56 Senegalese pol sequences using a Bayesian skyride plot in BEAST with relaxed uncorrelated lognormal molecular clock and moderately informative substitution rate prior (ucld.mean Normal: 2.5×10−3, 7.5×10−4). The X-axis represents the time in year. The Y-axis represents the HIV-1 effective number of infections (log10 scale). The black line marks the median estimate for Ne and the blue shadow region displays the 95% highest posterior density (HPD) interval.