Abstract This Chapter presents a variety of case studies of tongue root harmony in African languages. These case studies are arranged according to language family membership. The cases selected are those which have occupied a significant place in the theoretical literature. The objective is to demonstrate that the theory developed here can handle the cases that other theories have been built on: Niger-Congo (Yoruba), Nilo-Saharan (Maasai, Turkana), Afro-Asiatic (Somali, Kera) among many others. The RcvP model demonstrated that it can deal with all harmony patterns that were discussed, including most extra complications that individual systems exemplify.