Logo Lanfrica

Changes in lipid, liver, and renal profiles among patients with severe covid-19 during and after hospitalization at Saint Peter Specialized Hospital, Addis Ababa

Domaine:

healthcare

Type de record:

paper
Créateur:
WolWolBirHab
Éditeur:
Eth
Hôte:avatar
Background: COVID-19 progression affects multiple organ systems, and abnormalities in lipid, liver, and renal function tests have been reported. This study aimed to evaluate changes in organ function and lipid profiles among patients with severe COVID-19 during hospitalization and at discharge. Methods: A follow-up study was conducted at St. Peter Specialized Hospital from January 1 to April 30, 2021, involving 162 hospitalized COVID-19 patients. Five milliliters of venous blood were collected at admission and again at discharge. Lipid, renal, and liver function tests were performed using the Cobas 311 analyzer. Data were entered and analyzed using SPSS version 25. Results: Significant mean differences were observed in total cholesterol (20.13 mg/dL; 95% CI: 13.41–26.84; P < 0.001), HDL (7.53 mg/dL; 95% CI: 5.24–9.81; P < 0.001), and LDL (0.10 mg/dL; 95% CI: 0.06–0.14; P < 0.001) between admission and discharge. Albumin levels significantly increased at discharge, while ALT levels significantly decreased (P < 0.05). Conclusion: Dyslipidemia and hypoalbuminemia were observed during the acute phase of severe COVID-19. These findings suggest that severe COVID-19 induces significant alterations in lipid metabolism and liver function. Monitoring and managing lipid levels may improve clinical outcomes and reduce complications. Integrating lipid management into COVID-19 treatment protocols could enhance patient recovery and care effectiveness.

Tags

COVID-19Lipid profileLiver function testRenal function test

Licenses

Creative Commons Attribution Non Commercial 4.0 Internationalhttps://creativecommons.org/licenses/by-nc/4.0/legalcode

Similaires

Diabetic Patients’ Satisfaction of Teleconsultations and Associated Factors during COVID-19 Pandemic at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia

Abstract Background: Coronavirus disease 2019 (COVID-19) crisis increased the utilizatio

Table 1_Pattern, severity, and treatment outcomes in acute poisoning patients admitted to the Saint Peter Specialized Hospital Toxicology Center in Addis Ababa, Ethiopia, 2023: a retrospective study.docx

Background

Poisoning is a global public health problem that has more unfavorable outcomes in devel

Predictors of Treatment Outcomes among Pediatric Patients Hospitalized with Pneumonia in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia

Background. Pneumonia remains the leading cause of hospitalization and mortality in young children i

Stigma Resistance and Its Associated Factors among People with Bipolar Disorder at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia

Background . Stigma resistance is the capacity to cope and remain unaffected by mental illness stigm

Trends of follow-up clinic visits and admissions three-months before and during COVID-19 pandemic at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia: an interrupted time series analysis

Abstract Background Following the fi

Associations of institutional COVID-19 Mortality and Bacillus Calmette Guerin vaccination status in Tikur Anbessa Specialized Hospital COVID-19 Treatment Center, Addis Ababa, Ethiopia

The Data was Associations of institutional COVID-19 Mortality and Bacillus Calmette Guerin vaccinati