The data were collected among smallholder poultry farmers in Tanzania from March to April 2017. A total of 450 farmers were interviewed in GALVmed market development Newcastle Disease (ND) intervention areas, while100 farmers were interviewed in non-intervention areas. The main objective of the study was to assess whether there is any relationship in smallholder poultry production between the use of the ND vaccine and the wider use of other essential inputs and husbandry practices. The topics covered include poultry management, uses of ND vaccines, consumption, and income.