The Covid-19 pandemic is a pandemic of an emerging infectious disease, the 2019 coronavirus disease Covid-19, caused by the SARS-CoV-2 coronavirus. The essential protective measures recommended by WHO (2020) to limit the spread of the Coronavirus (Covid-19) limited in the suppression of travel, quarantine and containment. In the first part of this review, we will examine the origin of the coronavirus, the modes of spread and their adverse effects on human health. We will include in our analysis the nutritional importance of the different approaches based on mechanisms to boost the immune system and therefore good viral defense. The immune system helps protect the host against environmental agents such as pathogenic microorganisms (bacteria, fungi and viruses), thus preserving the integrity of the organism. To preserve the defense mechanisms of the organisms, an adequate nutritional state must be maintained with adequate intakes of calories, vitamins, minerals and water which must be continuously provided by a healthy diet. In addition, it is necessary to have nutritional information that will help boost the immune system of people in the fight against Covid-19, nutritional diagnosis and early nutritional management of affected patients must be integrated into the overall therapeutic strategy. Several clinical data have shown that micronutrients like vitamins, including vitamins A, C, D, E, B12, B6 and folic acid; trace elements like iron, zinc, copper, magnesium, selenium, and omega-3 fatty acids like docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) play a major role in supporting the immune system. Journal of Applied Science and Environmental Studies, Vol 5, No 1 (2022)