Corruption remains one of the most insidious impediments to Africa’s governance, development, and democratic consolidation. This chapter conceptualises corruption-proofing as a transformative framework for institutional resilience and systemic integrity. While previous scholarship has focused primarily on reactive legal mechanisms, this discussion advances a proactive systems-based approach centred on Accountability, Responsibility, Monitoring, and Sustainability (ARMS) as key principles of governance transformation. The chapter interrogates the enabling conditions of grand corruption – including elite capture, weak institutions, opaque political financing, and global complicity – and proposes a whole-of-society strategy to prevent, deter, and ultimately neutralise corruption. Using a comparative, doctrinal, and systems analysis methodology, the discussion synthesises existing legal instruments such as the African Union Convention on Preventing and Combating Corruption (AUCPCC) and the United Nations Convention Against Corruption (UNCAC), drawing from regional experiences and case studies across sub-Saharan Africa. The chapter concludes that corruption-proofing requires a holistic, people-centric paradigm termed ‘condemn and commend’, anchored in structural deterrence, ethical leadership, and multi-level accountability. By commending integrity and condemning illegality, dismantling kleptocratic structures, and incentivising ethical conduct, African states can reclaim public trust and repurpose diverted wealth toward inclusive growth. Corruption-proofing governance is not merely about preventing wrongdoing but about re-imagining governance as a moral enterprise grounded in justice, transparency, and collective prosperity. The study recommends strengthening diagonal accountability through the media and civil society, institutionalising supranational enforcement mechanisms, and embedding transparency and integrity within national systems.