Access to therapeutic oxygen remains a challenge in the effort to reduce
pneumonia mortality among children in low- and middle-income countries.
The use of oxygen concentrators is common, but their effectiveness in
delivering uninterrupted oxygen is gated by reliability of the power grid.
Often cylinders are employed to provide continuous coverage, but these can
present other logistical challenges. In this study, we examined the use of
a novel, low-pressure oxygen storage system to capture excess oxygen from
a concentrator to be delivered to patients during an outage. A prototype
was built and tested in a non-clinical trial in Jinja, Uganda. The trial
was carried out at Jinja Regional Referral Hospital over a 75-day period.
The flow rate of the unit was adjusted once per week between 0.5 and 5
liters per minute. Over the trial period, 1284 power failure episodes with
a mean duration of 3.1 minutes (range 0.08 to 1720 minutes) were recorded.
The low-pressure system was able to deliver oxygen over 56% of the 4,295
power outage minutes and cover over 99% of power outage events over the
course of the study. These results demonstrate the technical feasibility
of a method to extend oxygen availability and provide a basis for clinical
trials. Lab
DataLab testing
dataT66_tableau_data.xlsxperformance_cdfFigure 3 datapower_cdfFigure 3 dataPR0000001_filteredallPR0000001_filteredbyDayDaily measured parameters